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A Randomized Clinical Trial to Evaluate the Effects of Safinamide on Apathetic Non-demented Patients With Parkinson's Disease

BACKGROUND: Apathy is highly prevalent and disabling in Parkinson's disease (PD). Pharmacological options for its management lack sufficient evidence. OBJECTIVE: We studied the effects of safinamide on apathy in PD. METHODS: Prospective, 24-week, two-site, randomized, double-blind, placebo-cont...

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Detalles Bibliográficos
Autores principales: Kulisevsky, Jaime, Martínez-Horta, Saul, Campolongo, Antonia, Pascual-Sedano, Berta, Marín-Lahoz, Juan, Bejr-kasem, Helena, Aracil-Bolaños, Ignacio, Horta-Barba, Andrea, Puig-Davi, Arnau, Pagonabarraga, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201638/
https://www.ncbi.nlm.nih.gov/pubmed/35720066
http://dx.doi.org/10.3389/fneur.2022.866502