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Next Generation Risk Assessment of the Anti-Androgen Flutamide Including the Contribution of Its Active Metabolite Hydroxyflutamide
In next generation risk assessment (NGRA), non-animal approaches are used to quantify the chemical concentrations required to trigger bioactivity responses, in order to assure safe levels of human exposure. A limitation of many in vitro bioactivity assays, which are used in an NGRA context as new ap...
Autores principales: | van Tongeren, Tessa C.A., Carmichael, Paul L., Rietjens, Ivonne M.C.M., Li, Hequn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201820/ https://www.ncbi.nlm.nih.gov/pubmed/35722059 http://dx.doi.org/10.3389/ftox.2022.881235 |
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