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Increased Frequency of Indels in Hypervariable Regions of SARS-CoV-2 Proteins—A Possible Signature of Adaptive Selection
Most attention in the surveillance of evolving SARS-CoV-2 genome has been centered on nucleotide substitutions in the spike glycoprotein. We show that, as the pandemic extends into its second year, the numbers and ratio of genomes with in-frame insertions and deletions (indels) increases significant...
Autores principales: | Alisoltani, Arghavan, Jaroszewski, Lukasz, Iyer, Mallika, Iranzadeh, Arash, Godzik, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201826/ https://www.ncbi.nlm.nih.gov/pubmed/35719386 http://dx.doi.org/10.3389/fgene.2022.875406 |
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