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Effect of Multivalency on Phase-Separated Droplets Consisting of Poly(PR) Dipeptide Repeats and RNA at the Solid/Liquid Interface

[Image: see text] Dipeptide repeat proteins (DRPs) are considered a significant cause of amyotrophic lateral sclerosis (ALS), and their liquid–liquid phase separation (LLPS) formation with other biological molecules has been studied both in vitro and in vivo. The immobilization and wetting of the LL...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Jia, Han, Nakamura, Yoshiki, Kanekura, Kohsuke, Hayamizu, Yuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201888/
https://www.ncbi.nlm.nih.gov/pubmed/35721931
http://dx.doi.org/10.1021/acsomega.2c00811