Optimization of Automated Synthesis of Amide-Linked RNA

[Image: see text] The recent FDA approval of several antisense and siRNA drugs illustrates the utility of nucleic acid chemical modifications, but numerous challenges remain for generalized nucleic acid therapeutics, urging the exploration of new modification strategies. Replacing backbone phosphate...

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Detalles Bibliográficos
Autores principales: Viel, Julien A., Pal, Chandan, Rozners, Eriks
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201902/
https://www.ncbi.nlm.nih.gov/pubmed/35721988
http://dx.doi.org/10.1021/acsomega.2c02742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201902/
https://www.ncbi.nlm.nih.gov/pubmed/35721988
http://dx.doi.org/10.1021/acsomega.2c02742

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