Decoy Receptor 3 Suppresses T-Cell Priming and Promotes Apoptosis of Effector T-Cells in Acute Cell-Mediated Rejection: The Role of Reverse Signaling

BACKGROUND: Decoy receptor 3 (DcR3) belongs to the tumor necrosis factor (TNF) receptor superfamily and neutralizes TNF ligands, including FasL and TRAIL, to prevent T activation during T-cell priming. However, the cellular mechanisms underlying acute cell-mediated rejection (ACMR) remain unknown. M...

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Detalles Bibliográficos
Autores principales: Weng, Shuo-Chun, Wen, Mei-Chin, Hsieh, Shie-Liang, Chen, Nien-Jung, Tarng, Der-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201909/
https://www.ncbi.nlm.nih.gov/pubmed/35720343
http://dx.doi.org/10.3389/fimmu.2022.879648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201909/
https://www.ncbi.nlm.nih.gov/pubmed/35720343
http://dx.doi.org/10.3389/fimmu.2022.879648

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