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Decoy Receptor 3 Suppresses T-Cell Priming and Promotes Apoptosis of Effector T-Cells in Acute Cell-Mediated Rejection: The Role of Reverse Signaling
BACKGROUND: Decoy receptor 3 (DcR3) belongs to the tumor necrosis factor (TNF) receptor superfamily and neutralizes TNF ligands, including FasL and TRAIL, to prevent T activation during T-cell priming. However, the cellular mechanisms underlying acute cell-mediated rejection (ACMR) remain unknown. M...
Autores principales: | Weng, Shuo-Chun, Wen, Mei-Chin, Hsieh, Shie-Liang, Chen, Nien-Jung, Tarng, Der-Cherng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201909/ https://www.ncbi.nlm.nih.gov/pubmed/35720343 http://dx.doi.org/10.3389/fimmu.2022.879648 |
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