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Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis

OBJECTIVE: Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Mitochondrial dysfunction is suspected as one of the pathogenic mechanisms of PD. Growth/differentiation Factor-15 (GDF15) has been reported to affect mitochondrial function in PD. However, the relati...

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Detalles Bibliográficos
Autores principales: Li, Peizheng, Lv, Hongbo, Zhang, Bohan, Duan, Ruonan, Zhang, Xiufang, Lin, Pengfei, Song, Chengyuan, Liu, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201950/
https://www.ncbi.nlm.nih.gov/pubmed/35721026
http://dx.doi.org/10.3389/fnagi.2022.869558