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The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases

NLRP3 inflammasome is implicated in the pathogenesis of inflammatory bowel diseases (IBD). Since guanylate-binding protein 5 (GBP5) induces the NLRP3 inflammasome activity, we aim to investigate the potential role of GBP5 in IBD pathogenesis. The expression of GBP5, NLRP3 inflammasome, and related c...

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Detalles Bibliográficos
Autores principales: Li, Yichen, Lin, Xutao, Wang, Wenxia, Wang, Wenyu, Cheng, Sijing, Huang, Yibo, Zou, Yifeng, Ke, Jia, Zhu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201962/
https://www.ncbi.nlm.nih.gov/pubmed/35722277
http://dx.doi.org/10.3389/fmicb.2022.926915