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Kinetics of Nucleophilic Substitution of Compounds Containing Multiple Leaving Groups Bound to a Neopentyl Skeleton

[Image: see text] Ammonium salt derivatives with a neopentyl moiety are remarkably stable against Hofmann elimination, but the neopentyl moiety slows nucleophilic substitution, complicating their synthesis. To identify the best leaving group for the synthesis of the ammonium salts, we prepared six 1...

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Detalles Bibliográficos
Autores principales: Kasal, Petr, Jindřich, Jindřich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202039/
https://www.ncbi.nlm.nih.gov/pubmed/35721974
http://dx.doi.org/10.1021/acsomega.2c01965