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4-Chlorophenyl-N-furfuryl-1,2,4-triazole Methylacetamides as Significant 15-Lipoxygenase Inhibitors: an Efficient Approach for Finding Lead Anti-inflammatory Compounds

[Image: see text] Lipoxygenases (LOXs) are a class of enzymes that catalyze the production of pro-inflammatory mediators, such as leukotrienes and lipoxins, via an arachidonic acid cascade as soon as they are released from the membrane phospholipids after tissue injury. In continuation of our effort...

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Detalles Bibliográficos
Autores principales: Yasin, Muhammad, Shahid, Wardah, Ashraf, Muhammad, Saleem, Muhammad, Muzaffar, Saima, Aziz-ur-Rehman, Ejaz, Syed Abid, Saeed, Amna, Majer, Thomas, Bhattarai, Keshab, Riaz, Naheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202051/
https://www.ncbi.nlm.nih.gov/pubmed/35721976
http://dx.doi.org/10.1021/acsomega.2c01439