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Cavitation assisted endoplasmic reticulum targeted sonodynamic droplets to enhanced anti-PD-L1 immunotherapy in pancreatic cancer

BACKGROUND: Sonodynamic therapy (SDT) induces immunogenic cell death (ICD) in tumors and promises to play an assistive role in immunotherapy in pancreatic cancer. However, the short half-life and limited diffusion distance of reactive oxygen species (ROS) impair ICD induction, especially in tumors w...

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Detalles Bibliográficos
Autores principales: Chen, Jifan, Feng, Liting, Jin, Peile, Shen, Jiaxin, Lu, Jiayue, Song, Yue, Wang, Guowei, Chen, Qin, Huang, Deyi, Zhang, Ying, Zhang, Chao, Xu, Youfeng, Huang, Pintong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202099/
https://www.ncbi.nlm.nih.gov/pubmed/35710424
http://dx.doi.org/10.1186/s12951-022-01459-w