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A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity

BACKGROUND: Zika virus (ZIKV) and dengue virus (DENV) cause microcephaly and dengue hemorrhagic fever, respectively, leading to severe problems. No effective antiviral agents are approved against infections of these flaviviruses, calling for the need to develop potent therapeutics. We previously ide...

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Detalles Bibliográficos
Autores principales: Gao, Yaning, Tai, Wanbo, Wang, Xinyi, Jiang, Shibo, Debnath, Asim K., Du, Lanying, Chen, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202104/
https://www.ncbi.nlm.nih.gov/pubmed/35706035
http://dx.doi.org/10.1186/s12915-022-01344-w