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Risk of selection bias assessment in the NINDS rt-PA stroke study

OBJECTIVES: The NINDS rt-PA Stroke Study is frequently cited in support of alteplase for acute ischemic stroke within 3 h of symptom onset. Multiple post-hoc reanalyses of this trial have been published to adjust for a baseline imbalance in stroke severity. We performed a risk of selection bias asse...

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Detalles Bibliográficos
Autores principales: Garg, Ravi, Mickenautsch, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202115/
https://www.ncbi.nlm.nih.gov/pubmed/35705913
http://dx.doi.org/10.1186/s12874-022-01651-4