Cargando…

Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform

BACKGROUND: The Open Targets (OT) Platform integrates a wide range of data sources on target-disease associations to facilitate identification of potential therapeutic drug targets to treat human diseases. However, due to the complexity that targets are usually functionally pleiotropic and efficacio...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Yingnan, Klinger, Katherine, Rajpal, Deepak K., Zhu, Cheng, Teeple, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202116/
https://www.ncbi.nlm.nih.gov/pubmed/35710324
http://dx.doi.org/10.1186/s12859-022-04753-4