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Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform
BACKGROUND: The Open Targets (OT) Platform integrates a wide range of data sources on target-disease associations to facilitate identification of potential therapeutic drug targets to treat human diseases. However, due to the complexity that targets are usually functionally pleiotropic and efficacio...
Autores principales: | Han, Yingnan, Klinger, Katherine, Rajpal, Deepak K., Zhu, Cheng, Teeple, Erin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202116/ https://www.ncbi.nlm.nih.gov/pubmed/35710324 http://dx.doi.org/10.1186/s12859-022-04753-4 |
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