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Hypoxia-inducible factor expression is related to apoptosis and cartilage degradation in temporomandibular joint osteoarthritis

BACKGROUND: It remains unclear etiology of cartilaginous tissues in osteoarthritis (OA) lesions. In this study, we hypothesized the accumulation of hypoxia-inducible factor (HIF) and activated apoptosis relate to condylar cartilage degeneration in vivo. METHODS: Malocclusion stress was applied for 2...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Hu, Yu, Wang, Zihan, Wu, Xuelian, Yang, Chun, Yang, Hefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202126/
https://www.ncbi.nlm.nih.gov/pubmed/35710352
http://dx.doi.org/10.1186/s12891-022-05544-x