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GDF-11 promotes human trophoblast cell invasion by increasing ID2-mediated MMP2 expression

BACKGROUND: Growth differentiation factor-11 (GDF-11), also known as bone morphogenetic protein-11, belongs to the transforming growth factor-beta superfamily. GDF-11 was first identified as an important regulator during embryonic development. Increasing evidence has demonstrated that GDF-11 regulat...

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Detalles Bibliográficos
Autores principales: Wu, Ze, Fang, Lanlan, Yang, Sizhu, Gao, Yibo, Wang, Zhen, Meng, Qingxue, Dang, Xuan, Sun, Ying-Pu, Cheng, Jung-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202197/
https://www.ncbi.nlm.nih.gov/pubmed/35705978
http://dx.doi.org/10.1186/s12964-022-00899-z