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MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway

BACKGROUND: The development of drug resistance in oral squamous cell carcinoma (OSCC) that frequently leads to recurrence and metastasis after initial treatment remains an unresolved challenge. Presence of cancer stem cells (CSCs) has been increasingly reported to be a critical contributing factor i...

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Detalles Bibliográficos
Autores principales: Jang, Te-Hsuan, Huang, Wei-Chieh, Tung, Shiao-Lin, Lin, Sheng-Chieh, Chen, Po-Ming, Cho, Chun-Yu, Yang, Ya-Yu, Yen, Tzu-Chen, Lo, Guo-Hsuen, Chuang, Shuang-En, Wang, Lu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202219/
https://www.ncbi.nlm.nih.gov/pubmed/35706019
http://dx.doi.org/10.1186/s12929-022-00824-z