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Understanding the Mannose Transfer Mechanism of Mycobacterial Phosphatidyl-myo-inositol Mannosyltransferase A from Molecular Dynamics Simulations

[Image: see text] Glycolipids like phosphatidylinositol hexamannosides (PIM(6)) and lipoglycans, such as lipomannan (LM) and lipoarabinomannan (LAM), play crucial roles in virulence, survival, and antibiotic resistance of various mycobacterial species. Phosphatidyl-myo-inositol mannosyltransferase A...

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Detalles Bibliográficos
Autores principales: Bhattacharje, Gourab, Ghosh, Amit, Das, Amit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202250/
https://www.ncbi.nlm.nih.gov/pubmed/35721920
http://dx.doi.org/10.1021/acsomega.2c00832