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Catalytic Synthesis of 5-Fluoro-2-oxazolines: Using BF(3)·Et(2)O as the Fluorine Source and Activating Reagent

[Image: see text] Hypervalent iodine catalyst-catalyzed nucleophilic fluorination of unsaturated amides using BF(3)·Et(2)O as the fluorine source and activating reagent was reported. Various 5-fluoro-2-oxazoline derivatives were synthesized in good to excellent yields (up to 95% isolated yield) with...

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Detalles Bibliográficos
Autores principales: Chai, Hongli, Zhen, Xiang, Wang, Xueqing, Qi, Liang, Qin, Yuji, Xue, Jijun, Xu, Zhaoqing, Zhang, Hongrui, Zhu, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202255/
https://www.ncbi.nlm.nih.gov/pubmed/35721954
http://dx.doi.org/10.1021/acsomega.2c01791