Inhibition Mechanisms of (−)-Epigallocatechin-3-gallate and Genistein on Amyloid-beta 42 Peptide of Alzheimer’s Disease via Molecular Simulations

[Image: see text] The misfolding and self-assembly of amyloid-beta (Aβ) peptides are one of the most important factors contributing to Alzheimer’s disease (AD). This study aims to reveal the inhibition mechanisms of (−)-epigallocatechin-3-gallate (EGCG) and genistein on the conformational changes of...

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Detalles Bibliográficos
Autores principales: Fang, Mei, Zhang, Quan, Wang, Xin, Su, Kehe, Guan, Ping, Hu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202277/
https://www.ncbi.nlm.nih.gov/pubmed/35721940
http://dx.doi.org/10.1021/acsomega.2c01412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202277/
https://www.ncbi.nlm.nih.gov/pubmed/35721940
http://dx.doi.org/10.1021/acsomega.2c01412

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