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Inhibition Mechanisms of (−)-Epigallocatechin-3-gallate and Genistein on Amyloid-beta 42 Peptide of Alzheimer’s Disease via Molecular Simulations
[Image: see text] The misfolding and self-assembly of amyloid-beta (Aβ) peptides are one of the most important factors contributing to Alzheimer’s disease (AD). This study aims to reveal the inhibition mechanisms of (−)-epigallocatechin-3-gallate (EGCG) and genistein on the conformational changes of...
Autores principales: | Fang, Mei, Zhang, Quan, Wang, Xin, Su, Kehe, Guan, Ping, Hu, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202277/ https://www.ncbi.nlm.nih.gov/pubmed/35721940 http://dx.doi.org/10.1021/acsomega.2c01412 |
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