Direct Crystallization Resolution of Racemates Enhanced by Chiral Nanorods: Experimental, Statistical, and Quantum Mechanics/Molecular Dynamics Simulation Studies

[Image: see text] Three chiral nanorods of C(14)-l-Thea, C(14)-l-Phe, and C(14)-d-Phe were first synthesized and utilized as heterogeneous nucleants to enhance the resolution of racemic Asp via direct crystallization. Through the statistical analysis from 320 batches of nucleation experiments, we fo...

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Detalles Bibliográficos
Autores principales: Cao, Jiaojiao, Lou, Boxuan, Xu, Yue, Qin, Xiaolan, Yuan, Haikuan, Zhang, Lijuan, Zhang, Yan, Rohani, Sohrab, Lu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202296/
https://www.ncbi.nlm.nih.gov/pubmed/35722018
http://dx.doi.org/10.1021/acsomega.2c01596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202296/
https://www.ncbi.nlm.nih.gov/pubmed/35722018
http://dx.doi.org/10.1021/acsomega.2c01596

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