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Genetic suppressors of Δgrx3 Δgrx4, lacking redundant multidomain monothiol yeast glutaredoxins, rescue growth and iron homeostasis

Saccharomyces cerevisiae Grx3 and Grx4 are multidomain monothiol glutaredoxins that are redundant with each other. They can be efficiently complemented by heterologous expression of their mammalian ortholog, PICOT, which has been linked to tumor development and embryogenesis. PICOT is now believed t...

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Detalles Bibliográficos
Autores principales: Li, Guichun, Nanjaraj Urs, Ankanahalli N., Dancis, Andrew, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202360/
https://www.ncbi.nlm.nih.gov/pubmed/35593209
http://dx.doi.org/10.1042/BSR20212665