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Effects of Treatment With Hypnotics on Reduced Sleep Duration and Behavior Abnormalities in a Mouse Model of Fragile X Syndrome

Many patients with fragile X syndrome (FXS) have sleep disturbances, and Fmr1 knockout (KO) mice (a model of FXS) have reduced sleep duration compared to wild type (WT). Sleep is important for brain development, and chronic sleep restriction during development has long-lasting behavioral effects in...

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Detalles Bibliográficos
Autores principales: Saré, Rachel Michelle, Lemons, Abigail, Smith, Carolyn Beebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202518/
https://www.ncbi.nlm.nih.gov/pubmed/35720683
http://dx.doi.org/10.3389/fnins.2022.811528