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AlphaFold2 and RoseTTAFold predict posttranslational modifications. Chromophore formation in GFP-like proteins

AlphaFold2 and RoseTTAfold are able to predict, based solely on their sequence whether GFP-like proteins will post-translationally form a chromophore (the part of the protein responsible for fluorescence) or not. Their training has not only taught them protein structure and folding, but also chemist...

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Detalles Bibliográficos
Autores principales: Hartley, Sophia M., Tiernan, Kelly A., Ahmetaj, Gjina, Cretu, Adriana, Zhuang, Yan, Zimmer, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202861/
https://www.ncbi.nlm.nih.gov/pubmed/35709156
http://dx.doi.org/10.1371/journal.pone.0267560