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Renal functional, transcriptome, and methylome adaptations in pregnant Sprague Dawley and Brown Norway rats
Pregnancy induces maternal renal adaptations that include increased glomerular filtration rate and renal blood flow which can be compromised in obstetrical complications such as preeclampsia. Brown Norway (BN) rat pregnancies are characterized by placental insufficiency, maternal hypertension, and p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202892/ https://www.ncbi.nlm.nih.gov/pubmed/35709218 http://dx.doi.org/10.1371/journal.pone.0269792 |