Combined analyses of RNA-sequence and Hi-C along with GWAS loci—A novel approach to dissect keloid disorder genetic mechanism

Keloid disorder is a tumour-like disease with invasive growth and a high recurrence rate. Genetic contribution is well expected due to the presence of autosomal dominant inheritance and various genetic mutations in keloid lesions. However, GWAS failed to reveal functional variants in exon regions bu...

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Detalles Bibliográficos
Autores principales: Huang, Jia, Zhou, Xiaobo, Wang, Wenbo, Zhou, Guangdong, Zhang, WenJie, Gao, Zhen, Wu, Xiaoli, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202908/
https://www.ncbi.nlm.nih.gov/pubmed/35709140
http://dx.doi.org/10.1371/journal.pgen.1010168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202908/
https://www.ncbi.nlm.nih.gov/pubmed/35709140
http://dx.doi.org/10.1371/journal.pgen.1010168

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