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T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin
The reservoir of latently HIV-1 infected cells is heterogeneous. To achieve an HIV-1 cure, the reservoir of activatable proviruses must be eliminated while permanently silenced proviruses may be tolerated. We have developed a method to assess the proviral nuclear microenvironment in single cells. In...
Autores principales: | Lindqvist, Birgitta, Jütte, Bianca B., Love, Luca, Assi, Wlaa, Roux, Julie, Sönnerborg, Anders, Tezil, Tugsan, Verdin, Eric, Svensson, J. Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203004/ https://www.ncbi.nlm.nih.gov/pubmed/35666761 http://dx.doi.org/10.1371/journal.ppat.1010555 |
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