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Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks

Super-resolution imaging techniques have provided a better understanding of the relationship between the nanoscale organization and function of ryanodine receptors (RyRs) in cardiomyocytes. Recent data have indicated that this relationship is disrupted in heart failure (HF), as RyRs are dispersed in...

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Detalles Bibliográficos
Autores principales: Hernández Mesa, María, van den Brink, Jonas, Louch, William E., McCabe, Kimberly J., Rangamani, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203011/
https://www.ncbi.nlm.nih.gov/pubmed/35666763
http://dx.doi.org/10.1371/journal.pcbi.1010126