Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

Numerous receptor tyrosine kinases and immune receptors activate phospholipase C-γ (PLC-γ) isozymes at membranes to control diverse cellular processes including phagocytosis, migration, proliferation, and differentiation. The molecular details of this process are not well understood. Using hydrogen-...

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Detalles Bibliográficos
Autores principales: Siraliev-Perez, Edhriz, Stariha, Jordan TB, Hoffmann, Reece M, Temple, Brenda RS, Zhang, Qisheng, Hajicek, Nicole, Jenkins, Meredith L, Burke, John E, Sondek, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203054/
https://www.ncbi.nlm.nih.gov/pubmed/35708309
http://dx.doi.org/10.7554/eLife.77809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203054/
https://www.ncbi.nlm.nih.gov/pubmed/35708309
http://dx.doi.org/10.7554/eLife.77809

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