On demand expression control of endogenous genes with DExCon, DExogron and LUXon reveals differential dynamics of Rab11 family members

CRISPR technology has made generation of gene knock-outs widely achievable in cells. However, once inactivated, their re-activation remains difficult, especially in diploid cells. Here, we present DExCon (Doxycycline-mediated endogenous gene Expression Control), DExogron (DExCon combined with auxin-...

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Detalles Bibliográficos
Autores principales: Gemperle, Jakub, Harrison, Thomas S, Flett, Chloe, Adamson, Antony D, Caswell, Patrick T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203059/
https://www.ncbi.nlm.nih.gov/pubmed/35708998
http://dx.doi.org/10.7554/eLife.76651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203059/
https://www.ncbi.nlm.nih.gov/pubmed/35708998
http://dx.doi.org/10.7554/eLife.76651

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