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Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation

Increasing studies have identified the function of sirtuin-1 (SIRT1) in ocular diseases. Hence, this study is aimed at exploring the potential role of SIRT1 in choroidal neovascularization- (CNV-) induced age-related macular degeneration (AMD) development and the associated mechanism. Expression of...

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Detalles Bibliográficos
Autores principales: Zhao, Su, Huang, Zhi, Jiang, Hao, Xiu, Jiangfan, Zhang, Liying, Long, Qiurong, Yang, Yuhan, Yu, Lu, Lu, Lu, Gu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203240/
https://www.ncbi.nlm.nih.gov/pubmed/35720180
http://dx.doi.org/10.1155/2022/1671438