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Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation
Increasing studies have identified the function of sirtuin-1 (SIRT1) in ocular diseases. Hence, this study is aimed at exploring the potential role of SIRT1 in choroidal neovascularization- (CNV-) induced age-related macular degeneration (AMD) development and the associated mechanism. Expression of...
Autores principales: | Zhao, Su, Huang, Zhi, Jiang, Hao, Xiu, Jiangfan, Zhang, Liying, Long, Qiurong, Yang, Yuhan, Yu, Lu, Lu, Lu, Gu, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203240/ https://www.ncbi.nlm.nih.gov/pubmed/35720180 http://dx.doi.org/10.1155/2022/1671438 |
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