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Lysosome lipid signalling from the periphery to neurons regulates longevity

Lysosomes are key cellular organelles that metabolize extra- and intracellular substrates. Alterations in lysosomal metabolism are implicated in ageing-associated metabolic and neurodegenerative diseases. However, how lysosomal metabolism actively coordinates the metabolic and nervous systems to reg...

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Detalles Bibliográficos
Autores principales: Savini, Marzia, Folick, Andrew, Lee, Yi-Tang, Jin, Feng, Cuevas, André, Tillman, Matthew C., Duffy, Jonathon D., Zhao, Qian, Neve, Isaiah A., Hu, Pei-Wen, Yu, Yong, Zhang, Qinghao, Ye, Youqiong, Mair, William B., Wang, Jin, Han, Leng, Ortlund, Eric A., Wang, Meng C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203275/
https://www.ncbi.nlm.nih.gov/pubmed/35681008
http://dx.doi.org/10.1038/s41556-022-00926-8