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Lysosome lipid signalling from the periphery to neurons regulates longevity
Lysosomes are key cellular organelles that metabolize extra- and intracellular substrates. Alterations in lysosomal metabolism are implicated in ageing-associated metabolic and neurodegenerative diseases. However, how lysosomal metabolism actively coordinates the metabolic and nervous systems to reg...
Autores principales: | Savini, Marzia, Folick, Andrew, Lee, Yi-Tang, Jin, Feng, Cuevas, André, Tillman, Matthew C., Duffy, Jonathon D., Zhao, Qian, Neve, Isaiah A., Hu, Pei-Wen, Yu, Yong, Zhang, Qinghao, Ye, Youqiong, Mair, William B., Wang, Jin, Han, Leng, Ortlund, Eric A., Wang, Meng C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203275/ https://www.ncbi.nlm.nih.gov/pubmed/35681008 http://dx.doi.org/10.1038/s41556-022-00926-8 |
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