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Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
The first lineage choice in human embryo development separates trophectoderm from the inner cell mass. Naïve human embryonic stem cells are derived from the inner cell mass and offer possibilities to explore how lineage integrity is maintained. Here, we discover that polycomb repressive complex 2 (P...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203276/ https://www.ncbi.nlm.nih.gov/pubmed/35637409 http://dx.doi.org/10.1038/s41556-022-00916-w |