Iron commensalism of mesenchymal glioblastoma promotes ferroptosis susceptibility upon dopamine treatment

The heterogeneity of glioblastoma multiforme (GBM) leads to poor patient prognosis. Here, we aim to investigate the mechanism through which GBM heterogeneity is coordinated to promote tumor progression. We find that proneural (PN)-GBM stem cells (GSCs) secreted dopamine (DA) and transferrin (TF), in...

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Detalles Bibliográficos
Autores principales: Vo, Vu T. A., Kim, Sohyun, Hua, Tuyen N. M., Oh, Jiwoong, Jeong, Yangsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203457/
https://www.ncbi.nlm.nih.gov/pubmed/35710828
http://dx.doi.org/10.1038/s42003-022-03538-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203457/
https://www.ncbi.nlm.nih.gov/pubmed/35710828
http://dx.doi.org/10.1038/s42003-022-03538-y

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