Cargando…

Progressive aortic stiffness in aging C57Bl/6 mice displays altered contractile behaviour and extracellular matrix changes

Aortic stiffness is a hallmark of cardiovascular disease, but its pathophysiology remains incompletely understood. This study presents an in-dept characterization of aortic aging in male C57Bl/6 mice (2–24 months). Cardiovascular measurements include echocardiography, blood pressure measurement, and...

Descripción completa

Detalles Bibliográficos
Autores principales: De Moudt, Sofie, Hendrickx, Jhana O., Neutel, Cédric, De Munck, Dorien, Leloup, Arthur, De Meyer, Guido R. Y., Martinet, Wim, Fransen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203497/
https://www.ncbi.nlm.nih.gov/pubmed/35710942
http://dx.doi.org/10.1038/s42003-022-03563-x