Daisaikoto improves fatty liver and obesity in melanocortin-4 receptor gene-deficient mice via the activation of brown adipose tissue

Melanocortin 4 receptor gene-knockout (MC4R-KO) mice are known to develop obesity with a high-fat diet. Meanwhile, daisaikoto, one of Kampo medicines, is a drug that is expected to have therapeutic effects on obesity. Here, we report the efficacy of daisaikoto in MC4R-KO mice. Eight-week-old MC4R-KO...

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Detalles Bibliográficos
Autores principales: Morita, Shinichi, Sakamaki, Akira, Koyama, Kyutaro, Shibata, Osamu, Owaki, Takashi, Oda, Chiyumi, Kimura, Atsushi, Nakaya, Taiki, Ohbuchi, Katsuya, Nahata, Miwa, Fujitsuka, Naoki, Sakai, Norihiro, Abe, Hiroyuki, Kamimura, Kenya, Terai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203505/
https://www.ncbi.nlm.nih.gov/pubmed/35710868
http://dx.doi.org/10.1038/s41598-022-14371-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203505/
https://www.ncbi.nlm.nih.gov/pubmed/35710868
http://dx.doi.org/10.1038/s41598-022-14371-y

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