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Phasing analysis of lung cancer genomes using a long read sequencer

Chromosomal backgrounds of cancerous mutations still remain elusive. Here, we conduct the phasing analysis of non-small cell lung cancer specimens of 20 Japanese patients. By the combinatory use of short and long read sequencing data, we obtain long phased blocks of 834 kb in N50 length with >99%...

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Detalles Bibliográficos
Autores principales: Sakamoto, Yoshitaka, Miyake, Shuhei, Oka, Miho, Kanai, Akinori, Kawai, Yosuke, Nagasawa, Satoi, Shiraishi, Yuichi, Tokunaga, Katsushi, Kohno, Takashi, Seki, Masahide, Suzuki, Yutaka, Suzuki, Ayako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203510/
https://www.ncbi.nlm.nih.gov/pubmed/35710642
http://dx.doi.org/10.1038/s41467-022-31133-6