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From CD16a Biology to Antibody-Dependent Cell-Mediated Cytotoxicity Improvement
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent cytotoxic mechanism that is mainly mediated in humans by natural killer (NK) cells. ADCC mediates the clinical benefit of several widely used cytolytic monoclonal antibodies (mAbs), and increasing its efficacy would improve cancer immu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203678/ https://www.ncbi.nlm.nih.gov/pubmed/35720368 http://dx.doi.org/10.3389/fimmu.2022.913215 |