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From CD16a Biology to Antibody-Dependent Cell-Mediated Cytotoxicity Improvement

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent cytotoxic mechanism that is mainly mediated in humans by natural killer (NK) cells. ADCC mediates the clinical benefit of several widely used cytolytic monoclonal antibodies (mAbs), and increasing its efficacy would improve cancer immu...

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Detalles Bibliográficos
Autores principales: Coënon, Loïs, Villalba, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203678/
https://www.ncbi.nlm.nih.gov/pubmed/35720368
http://dx.doi.org/10.3389/fimmu.2022.913215