Cargando…

Pegylated Insulin-Like Growth Factor 1 attenuates Hair Cell Loss and promotes Presynaptic Maintenance of Medial Olivocochlear Cholinergic Fibers in the Cochlea of the Progressive Motor Neuropathy Mouse

The progressive motor neuropathy (PMN) mouse is a model of an inherited motor neuropathy disease with progressive neurodegeneration. Axon degeneration associates with homozygous mutations of the TBCE gene encoding the tubulin chaperone E protein. TBCE is responsible for the correct dimerization of a...

Descripción completa

Detalles Bibliográficos
Autores principales: Bieniussa, Linda, Kahraman, Baran, Skornicka, Johannes, Schulte, Annemarie, Voelker, Johannes, Jablonka, Sibylle, Hagen, Rudolf, Rak, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203726/
https://www.ncbi.nlm.nih.gov/pubmed/35720065
http://dx.doi.org/10.3389/fneur.2022.885026