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Pegylated Insulin-Like Growth Factor 1 attenuates Hair Cell Loss and promotes Presynaptic Maintenance of Medial Olivocochlear Cholinergic Fibers in the Cochlea of the Progressive Motor Neuropathy Mouse
The progressive motor neuropathy (PMN) mouse is a model of an inherited motor neuropathy disease with progressive neurodegeneration. Axon degeneration associates with homozygous mutations of the TBCE gene encoding the tubulin chaperone E protein. TBCE is responsible for the correct dimerization of a...
Autores principales: | Bieniussa, Linda, Kahraman, Baran, Skornicka, Johannes, Schulte, Annemarie, Voelker, Johannes, Jablonka, Sibylle, Hagen, Rudolf, Rak, Kristen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203726/ https://www.ncbi.nlm.nih.gov/pubmed/35720065 http://dx.doi.org/10.3389/fneur.2022.885026 |
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