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Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue

Direct activation of cell-surface receptors is highly desirable for elucidating their physiological roles. A potential approach for cell-type-specific activation of a receptor subtype is chemogenetics, in which both point mutagenesis of the receptors and designed ligands are used. However, ligand-bi...

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Detalles Bibliográficos
Autores principales: Ojima, Kento, Kakegawa, Wataru, Yamasaki, Tokiwa, Miura, Yuta, Itoh, Masayuki, Michibata, Yukiko, Kubota, Ryou, Doura, Tomohiro, Miura, Eriko, Nonaka, Hiroshi, Mizuno, Seiya, Takahashi, Satoru, Yuzaki, Michisuke, Hamachi, Itaru, Kiyonaka, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203742/
https://www.ncbi.nlm.nih.gov/pubmed/35710788
http://dx.doi.org/10.1038/s41467-022-30828-0