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Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue
Direct activation of cell-surface receptors is highly desirable for elucidating their physiological roles. A potential approach for cell-type-specific activation of a receptor subtype is chemogenetics, in which both point mutagenesis of the receptors and designed ligands are used. However, ligand-bi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203742/ https://www.ncbi.nlm.nih.gov/pubmed/35710788 http://dx.doi.org/10.1038/s41467-022-30828-0 |