Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells

Receptor tyrosine kinase inhibitors improve cancer survival but their cardiotoxicity requires investigation. We investigated these inhibitors’ effects on human cardiac progenitor cells in vitro and rat heart in vivo. We applied imatinib, sunitinib or sorafenib to human cardiac progenitor cells, asse...

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Detalles Bibliográficos
Autores principales: Smith, Andrew J., Ruchaya, Prashant, Walmsley, Robert, Wright, Kathleen E., Lewis-McDougall, Fiona C., Bond, Jacquelyn, Ellison-Hughes, Georgina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203790/
https://www.ncbi.nlm.nih.gov/pubmed/35710779
http://dx.doi.org/10.1038/s41598-022-13203-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203790/
https://www.ncbi.nlm.nih.gov/pubmed/35710779
http://dx.doi.org/10.1038/s41598-022-13203-3

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