Cargando…
Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells
Receptor tyrosine kinase inhibitors improve cancer survival but their cardiotoxicity requires investigation. We investigated these inhibitors’ effects on human cardiac progenitor cells in vitro and rat heart in vivo. We applied imatinib, sunitinib or sorafenib to human cardiac progenitor cells, asse...
Autores principales: | Smith, Andrew J., Ruchaya, Prashant, Walmsley, Robert, Wright, Kathleen E., Lewis-McDougall, Fiona C., Bond, Jacquelyn, Ellison-Hughes, Georgina M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203790/ https://www.ncbi.nlm.nih.gov/pubmed/35710779 http://dx.doi.org/10.1038/s41598-022-13203-3 |
Ejemplares similares
-
Transplantation of Skeletal Muscle-Derived Sca-1(+)/PW1(+)/Pax7(−) Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction
por: Ruchaya, Prashant J, et al.
Publicado: (2022) -
Aged‐senescent cells contribute to impaired heart regeneration
por: Lewis‐McDougall, Fiona C., et al.
Publicado: (2019) -
Role of stem/progenitor cells in reparative disorders
por: Pretheeban, Thavaneetharajah, et al.
Publicado: (2012) -
Reparative macrophage transplantation for myocardial repair: a refinement of bone marrow mononuclear cell-based therapy
por: Podaru, Mihai-Nicolae, et al.
Publicado: (2019) -
Imatinib Mesylate Induces Necroptotic Cell Death and Impairs Autophagic Flux in Human Cardiac Progenitor Cells
por: Walmsley, Robert, et al.
Publicado: (2022)