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Exhausted PD-1(+) TOX(+) CD8(+) T Cells Arise Only in Long-Term Experimental Trypanosoma cruzi Infection

Infection with Trypanosoma cruzi remains the most important neglected zoonosis in Latin America. This infection does not lead to specific symptoms in the acute phase, but chronic infection can result in Chagas disease (CD) with cardiac and/or gastrointestinal manifestations that can lead to death. C...

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Detalles Bibliográficos
Autores principales: Gálvez, Rosa Isela, Jacobs, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203896/
https://www.ncbi.nlm.nih.gov/pubmed/35720419
http://dx.doi.org/10.3389/fimmu.2022.866179